Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Staphylococcus aureus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0491 | - |
9,10-phenanthrenequinone | pH 7.5, 25°C | Staphylococcus aureus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
36300 | - |
x * 36300, calculated and co-purification results | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | A0A0H3JVE7 | - |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
14.8 | - |
substrate menadione, pH 7.5, 25°C | Staphylococcus aureus |
311 | - |
substrate 9,10-phenanthrenequinone, pH 7.5, 25°C | Staphylococcus aureus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
9,10-phenanthrenequinone + NADPH + H+ | one-electron reduction mechanism. Concomitantly with NADPH consumption, generation of superoxide is observed | Staphylococcus aureus | 9,10-phenanthrenequinol + NADP+ | - |
? | |
menadione + NADPH + H+ | - |
Staphylococcus aureus | menadiol + NADP+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
multimer | x * 36300, calculated and co-purification results | Staphylococcus aureus |
Synonyms | Comment | Organism |
---|---|---|
QorA | - |
Staphylococcus aureus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | no cofactor: NADH. Sequence does not contain a flavin-binding motif | Staphylococcus aureus | |
NADPH | - |
Staphylococcus aureus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Staphylococcus aureus | calculated | - |
5.2 |
Organism | Comment | Expression |
---|---|---|
Staphylococcus aureus | induced in presence of 9,10-phenanthrenequinone and by oxidative stress | up |