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Literature summary for 1.6.5.9 extracted from
- Diversity and origin of alternative NADH:ubiquinone oxidoreductases (2000), Biochim. Biophys. Acta, 1459, 274-283.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | NADH oxidation is completely insensitive to amytal and rotenone | Saccharomyces pastorianus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrial membrane | - |
Saccharomyces pastorianus | 31966 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces pastorianus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + H+ + ubiquinone | - |
Saccharomyces pastorianus | NAD+ + ubiquinol | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alternative NADH:ubiquinone oxidoreductase | - |
Saccharomyces pastorianus |
| internal alternative NADH:ubiquinone oxidoreductase | - |
Saccharomyces pastorianus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Saccharomyces pastorianus | |
| additional information | the enzyme lacks iron-sulfur clusters | Saccharomyces pastorianus | |
| NADH | - |
Saccharomyces pastorianus | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | internal alternative NADH:ubiquinone oxidoreductase is the only enzyme capable of feeding NADH generated in the mitochondrial matrix into the respiratory chain | Saccharomyces pastorianus |
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