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Literature summary for 1.7.1.10 extracted from

  • Kadlubar, F.F.; Mckee, E.M.; Ziegler, D.M.
    Reduced pyridine nucleotide-dependent N-hydroxy amine oxidase and reductase activities of hepatic microsomes (1973), Arch. Biochem. Biophys., 156, 46-57.
    View publication on PubMed
Search for more literature for 1.7.1.10

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by 0.1 mM KCN, NaN3, EDTA, CO and O2 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Sus scrofa
-
-

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
 microsomal multicomponent enzyme system consisting of NADH, cytochrome b5, cytochrome b5 reductase and a third unidentified protein, catalyzes reduction of hydroxylamine and a number of its mono- and disubstituted derivatives
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Sus scrofa
-
liver
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hydroxylamine + NADH
-
 Sus scrofa NH3 + NAD+ + H2O
-
 ?
N,N-dimethylhydroxylamine + NADH
-
 Sus scrofa dimethylamine + NAD+ + H2O
-
 ?
N-hydroxyamphetamine + NADH
-
 Sus scrofa amphetamine + NAD+ + H2O
-
 ?
N-hydroxypiperidine + NADH
-
 Sus scrofa piperidine + NAD+ + H2O
-
 ?
N-methyl-N-benzyl-hydroxylamine + NADH
-
 Sus scrofa N-methylbenzylamine + NAD+ + H2O
-
 ?
N-methyl-N-n-octyl-hydroxylamine + NADH
-
 Sus scrofa N-methyl-n-octylamine + NAD+ + H2O
-
 ?
N-methylhydroxylamine + NADH
-
 Sus scrofa methylamine + NAD+ + H2O
-
 ?
phenylhydroxylamine + NADH
-
 Sus scrofa phenylamine + NAD+ + H2O
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.3
-
-
 Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Sus scrofa