Application | Comment | Organism |
---|---|---|
environmental protection | hexahydro-1,3,5-trinitro-1,3,5-triazine is widely used for military and commercial purposes due to its high explosive properties. Hexahydro-1,3,5-trinitro-1,3,5-triazine and its degradation products are toxic, mutagenic and carcinogenic to humans and other biological systems. The biotransformation of hexahydro-1,3,5-trinitro-1,3,5-triazine by NAD(P)H nitrate reductase from Aspergillus niger under anaerobic conditions | Aspergillus niger |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus niger | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hexahydro-1,3,5-trinitro-1,3,5-triazine + NADPH | - |
Aspergillus niger | hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine + NADP+ | hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine is the first reduced product formed by a two-electron reduction mechanism. Subsequent reduction of hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine followed by rapid ring cleavage gives methylenedinitramine which in turn decomposes in water to N2O, NH4+ and HCHO | ? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
biotransformation of hexahydro-1,3,5-trinitro-1,3,5-triazine | Aspergillus niger |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
biotransformation of hexahydro-1,3,5-trinitro-1,3,5-triazine | Aspergillus niger |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Aspergillus niger |