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Literature summary for 1.7.1.7 extracted from

  • Ji, C.N.; Ying, G.; Deng, Y.F.; Chen, S.; Zhang, W.H.; Shu, G.; Xie, Y.; Mao, Y.M.
    Purification, crystallization and preliminary X-ray studies of GMP reductase 2 from human (2003), Acta Crystallogr. Sect. D, 59, 1109-1110.
    View publication on PubMed
Search for more literature for 1.7.1.7

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli M15 as His-tag fusion protein Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging-drop vapor diffusion method Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADPH + guanosine 5'-phosphate Homo sapiens essential for the salvage pathway of purine ribonucleotide biosynthesis NADP+ + inosine 5'-phosphate + NH3
-
 ir

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme using His-tag Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADPH + guanosine 5'-phosphate
-
 Homo sapiens NADP+ + inosine 5'-phosphate + NH3
-
 ir
NADPH + guanosine 5'-phosphate essential for the salvage pathway of purine ribonucleotide biosynthesis Homo sapiens NADP+ + inosine 5'-phosphate + NH3
-
 ir

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Homo sapiens