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BRENDA support

Literature summary for 1.7.1.9 extracted from

  • Stanley, J.S.; York, J.L.; Benson, a.M.
    Nitroreductases and glutathione transferases that act on 4-nitroquinoline 1-oxide and their differential induction by butylated hydroxyanisole in mice (1992), Cancer Res., 52, 58-63.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by dicoumarol Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.015
-
4-Nitroquinoline N-oxide
-
Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
200000
-
-
Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitroquinoline N-oxide + NAD(P)H + H+ strong preference for NADH Mus musculus 4-(hydroxyamino)quinoline N-oxide + NAD(P)+ + H2O
-
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