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Literature summary for 1.7.2.3 extracted from

  • Bordi, C.; Iobbi-Nivol, C.; Mejean, V.; Patte, J.C.
    Effects of ISSo2 insertions in structural and regulatory genes of the trimethylamine oxide reductase of Shewanella oneidensis (2003), J. Bacteriol., 185, 2042-2045.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information isolation of Shewanella oneidensis mutants, showing impaired trimethylamine oxide respiration due to mutations by ISSo2 insertions in gene torA, gene torR, and gene torS, the 2 latter encoding the regulator TorR and sensor TorS, overview Shewanella oneidensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Shewanella oneidensis regulator TorR and sensor TorS, encoded by genes torR and torS in the same operon as torA, are required for the trimethylamine oxide respiration pathway ?
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?
trimethylamine N-oxide + NADH Shewanella oneidensis enzyme is highly specific for trimethylamine oxide as alternative terminal electron acceptor NAD+ + trimethylamine + H2O
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?

Organism

Organism UniProt Comment Textmining
Shewanella oneidensis
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gene torA encoded in the torECAD operon of the tor locus, wild-type strain MR1 ATCC 700550 and rifampicin-resistant derivative
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information regulator TorR and sensor TorS, encoded by genes torR and torS in the same operon as torA, are required for the trimethylamine oxide respiration pathway Shewanella oneidensis ?
-
?
trimethylamine N-oxide + NADH enzyme is highly specific for trimethylamine oxide as alternative terminal electron acceptor Shewanella oneidensis NAD+ + trimethylamine + H2O
-
?
trimethylamine N-oxide + NADH enzyme is highly specific for trimethylamine oxide as electron acceptor Shewanella oneidensis NAD+ + trimethylamine + H2O trimethylamine is volatile ?

Synonyms

Synonyms Comment Organism
TMAO reductase
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Shewanella oneidensis
TorA
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Shewanella oneidensis
trimethylamine oxide reductase
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Shewanella oneidensis

Cofactor

Cofactor Comment Organism Structure
molybdenum cofactor
-
Shewanella oneidensis