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Literature summary for 1.7.3.3 extracted from

  • Leal-Pinto, E.; London, R.D.; Knorr, B.A.; Abramson, R.G.
    Reconstitution of hepatic uricase in planar lipid bilayer reveals a functional organic anion channel (1995), J. Membr. Biol., 146, 123-132.
    View publication on PubMed
Search for more literature for 1.7.3.3

Inhibitors

Inhibitors Comment Organism Structure
pyrazinoate channel activity completely disappears Rattus norvegicus
pyrazinoate channel activity completely disappears Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
cell membrane
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
urate + O2 + H2O Rattus norvegicus
-
 5-hydroxyisourate + H2O2
-
 ?
urate + O2 + H2O Sus scrofa
-
 5-hydroxyisourate + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
liver
-
 Sus scrofa
-
proximal tubule
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information uricase can function as a voltage-sensitive channel that is highly selective to urate, relative to K+ and Cl- Rattus norvegicus ?
-
 ?
additional information uricase can function as a voltage-sensitive channel that is highly selective to urate, relative to K+ and Cl- Sus scrofa ?
-
 ?
urate + O2 + H2O
-
 Rattus norvegicus 5-hydroxyisourate + H2O2
-
 ?
urate + O2 + H2O
-
 Sus scrofa 5-hydroxyisourate + H2O2
-
 ?