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Literature summary for 1.8.1.10 extracted from

  • Dyar, R.E.; Wilken, D.R.
    Rat liver levels of coenzyme A-glutathione and of enzymes in its metabolism (1972), Arch. Biochem. Biophys., 153, 619-626.
    View publication on PubMed
Search for more literature for 1.8.1.10

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CoA-glutathione + NADPH Rattus norvegicus may be important in metabolism of CoASSG glutathione + CoA + NADP+
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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 male albino, normal and alloxan diabetic rats, no change of enzyme activity and CoASSG content in diabetic rats
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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 Rattus norvegicus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0007
-
 alloxan diabetic rats, liver extract Rattus norvegicus
0.00085
-
 normal rats, liver extract Rattus norvegicus

Storage Stability

Storage Stability Organism
4°C, dialyzed extract, 16 hours, stable Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CoA-glutathione + NADPH
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 Rattus norvegicus glutathione + CoA + NADP+
-
 ?
CoA-glutathione + NADPH may be important in metabolism of CoASSG Rattus norvegicus glutathione + CoA + NADP+
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADPH NADPH-dependent Rattus norvegicus