Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Sus scrofa | 5829 | - |
microsome | - |
Sus scrofa | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | highly stimulating for ubiquinone reduction | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
2 * 55000, about, SDS-PAGE | Sus scrofa |
115000 | - |
gel filtration | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ubiquinone + NAD(P)H | Sus scrofa | enzyme is involved in extramitochondrial regeneration of the important antioxidant ubiquinol required for cell protection against peroxidation | ubiquinol + NAD(P)+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Sus scrofa | - |
heart | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ubiquinone + NAD(P)H | - |
Sus scrofa | ubiquinol + NAD(P)+ | - |
? | |
ubiquinone + NAD(P)H | enzyme is involved in extramitochondrial regeneration of the important antioxidant ubiquinol required for cell protection against peroxidation | Sus scrofa | ubiquinol + NAD(P)+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 55000, about, SDS-PAGE | Sus scrofa |
Synonyms | Comment | Organism |
---|---|---|
DT-diaphorase | - |
Sus scrofa |
LipDH | - |
Sus scrofa |
lipoamide dehydrogenase | - |
Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
highest activity at acidic pH | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | flavoenzyme, 1 FAD per enzyme subunit, functionally important | Sus scrofa | |
additional information | enzyme contains 1 disulfide/dithiol per subunit | Sus scrofa | |
NAD(P)H | NADPH and NADH are equally effective as cofactors | Sus scrofa |