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Literature summary for 1.8.1.9 extracted from

  • Huber, K.; Patel, P.; Zhang, L.; Evans, H.; Westwell, A.D.; Fischer, P.M.; Chan, S.; Martin, S.
    2-[(1-methylpropyl)dithio]-1H-imidazole inhibits tubulin polymerization through cysteine oxidation (2008), Mol. Cancer Ther., 7, 143-151.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information 2-[(1-methylpropyl)dithio]-1H-imidazole (IV-2) causes the oxidation of cysteine residues from both thioredoxin reductase and thioredoxin, with only the latter leading to irreversible inhibition of protein function Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HUVEC cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
thioredoxin reductase
-
Homo sapiens