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Literature summary for 1.8.3.1 extracted from

  • Woo, W.H.; Yang, H.; Wong, K.P.; Halliwell, B.
    Sulphite oxidase gene expression in human brain and in other human and rat tissues (2003), Biochem. Biophys. Res. Commun., 305, 619-623.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sulfite + O2 + H2O Homo sapiens lack of active enzyme produces severe neurodegeneration and early death in humans sulfate + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-
brain expression in all brain regions examined: cerebellum, cerebral cortex, medulla, spinal cord, ocipital pole, frontal lobe, amygdala, caudate nucleus, corpus callosum, hippocampus, thalamus, temporal lobe, putamen. The cerebral cortex shows the highest level of expression Homo sapiens
-
colon little expression Homo sapiens
-
heart
-
Rattus norvegicus
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heart substantial expression Homo sapiens
-
kidney
-
Rattus norvegicus
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kidney substantial expression Homo sapiens
-
leukocyte perpheral blood, little expression Homo sapiens
-
liver strong activity Rattus norvegicus
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liver substantial expression Homo sapiens
-
lung
-
Rattus norvegicus
-
lung little expression Homo sapiens
-
peripheral blood leucocyte, little expression Homo sapiens
-
placenta substantial expression Homo sapiens
-
skeletal muscle substantial expression Homo sapiens
-
small intestine little expression Homo sapiens
-
spleen little expression Homo sapiens
-
thymus little expression Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sulfite + O2 + H2O
-
Homo sapiens sulfate + H2O2
-
?
sulfite + O2 + H2O
-
Rattus norvegicus sulfate + H2O2
-
?
sulfite + O2 + H2O lack of active enzyme produces severe neurodegeneration and early death in humans Homo sapiens sulfate + H2O2
-
?