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Literature summary for 1.8.3.2 extracted from

  • Chakravarthi, S.; Jessop, C.E.; Willer, M.; Stirling, C.J.; Bulleid, N.J.
    Intracellular catalysis of disulfide bond formation by the human sulfhydryl oxidase, QSOX1 (2007), Biochem. J., 404, 403-411.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
additional information overexpression of QSOX1a suppresses the lethality of a complete deletion of endoplasmic reticulum oxidase 1 in yeast and restores disulfide bond formation. The enzyme has a minimal role in catalysis of disulfide bonds within the endoplasmic reticulum Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
CHO-tPA cell-line stably expressing QSOX1-V5 with a C-terminal KDEL sequence Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus QSOX1a-V5 is a glycosylated, transmembrane protein localized to the Golgi apparatus Homo sapiens 5794
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Organism

Organism UniProt Comment Textmining
Homo sapiens O00391
-
-

Synonyms

Synonyms Comment Organism
QSOx1
-
Homo sapiens
sulfhydryl oxidase
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Homo sapiens