Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | the myristoylated enzyme form is found in cytosol | Mus musculus | 5829 | - |
membrane | - |
Mus musculus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-methionine (S)-sulfoxide + dithiothreitol | Mus musculus | the myristoylated enzyme form reduces methionine sulfoxide in protein much faster than the nonmyristoylated form | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
lipoprotein | myristoylation | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
apolipoprotein A-I + dithiothreitol | the myristoylated enzyme reduces the methionine sulfoxides in apolipoprotein A-I four times faster than nonmyristoylated enzyme | Mus musculus | ? | - |
? | |
L-methionine (S)-sulfoxide + dithiothreitol | the myristoylated enzyme form reduces methionine sulfoxide in protein much faster than the nonmyristoylated form | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
methionine sulfoxide reductase A | - |
Mus musculus |
MsrA | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thioredoxin | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
metabolism | methionine sulfoxide reductase A is an essential enzyme in the antioxidant system which scavenges reactive oxygen species through cyclic oxidation and reduction of methionine and methionine sulfoxide | Mus musculus |