Activating Compound | Comment | Organism | Structure |
---|---|---|---|
deoxycholate | activating the enzyme membrane-bound in the microsomal fraction | Rattus norvegicus | |
Triton X-100 | activating the enzyme membrane-bound in the microsomal fraction | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
deoxycholate | - |
Bos taurus | |
deoxycholate | inhibitory for the solubilized enzyme | Rattus norvegicus | |
lysolecithin | - |
Bos taurus | |
lysolecithin | - |
Homo sapiens | |
lysolecithin | - |
Rattus norvegicus | |
phosphatidic acid | - |
Bos taurus | |
phosphatidic acid | - |
Homo sapiens | |
phosphatidic acid | - |
Rattus norvegicus | |
Triton X-100 | inhibitory for the solubilized enzyme | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
2 glutathione + protein-disulfide = glutathione-disulfide + protein-dithiol | random and allosteric mechanism via multiple distinct reaction sites | Homo sapiens | |
2 glutathione + protein-disulfide = glutathione-disulfide + protein-dithiol | random and allosteric mechanism via multiple distinct reaction sites | Rattus norvegicus | |
2 glutathione + protein-disulfide = glutathione-disulfide + protein-dithiol | random and allosteric mechanism via multiple distinct reaction sites | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Homo sapiens | - |
heart | - |
Rattus norvegicus | - |
heart | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GSH + insulin | proinsulin | Homo sapiens | GSSG + reduced insulin chain A and B | - |
? | |
GSH + insulin | proinsulin | Rattus norvegicus | GSSG + reduced insulin chain A and B | - |
? | |
GSH + insulin | proinsulin | Bos taurus | GSSG + reduced insulin chain A and B | - |
? | |
GSH + oxytoxin | - |
Homo sapiens | ? | - |
? | |
GSH + oxytoxin | - |
Rattus norvegicus | ? | - |
? | |
GSH + oxytoxin | - |
Bos taurus | ? | - |
? | |
GSH + protein disulfide | - |
Homo sapiens | GSSG + protein-dithiol | - |
? | |
GSH + protein disulfide | - |
Rattus norvegicus | GSSG + protein-dithiol | - |
? | |
GSH + protein disulfide | - |
Bos taurus | GSSG + protein-dithiol | - |
? | |
GSH + vasopressin | - |
Homo sapiens | ? | - |
? | |
GSH + vasopressin | - |
Rattus norvegicus | ? | - |
? | |
GSH + vasopressin | - |
Bos taurus | ? | - |
? | |
additional information | the two activities, cleavage and formation of protein-disulfide bonds, present alternate activities of the same enzyme | Homo sapiens | ? | - |
? | |
additional information | the two activities, cleavage and formation of protein-disulfide bonds, present alternate activities of the same enzyme | Rattus norvegicus | ? | - |
? | |
additional information | the two activities, cleavage and formation of protein-disulfide bonds, present alternate activities of the same enzyme | Bos taurus | ? | - |
? | |
additional information | immunoglobulin IgM and IgG | Homo sapiens | ? | - |
? | |
additional information | immunoglobulin IgM and IgG | Rattus norvegicus | ? | - |
? | |
additional information | immunoglobulin IgM and IgG | Bos taurus | ? | - |
? | |
additional information | scrambled lysozyme | Homo sapiens | ? | - |
? | |
additional information | scrambled lysozyme | Rattus norvegicus | ? | - |
? | |
additional information | scrambled lysozyme | Bos taurus | ? | - |
? | |
additional information | scrambled trypsin inhibitor and proinsulin | Homo sapiens | ? | - |
? | |
additional information | scrambled trypsin inhibitor and proinsulin | Rattus norvegicus | ? | - |
? | |
additional information | scrambled trypsin inhibitor and proinsulin | Bos taurus | ? | - |
? | |
additional information | thiol:protein-disulfide oxidoreductase EC 1.8.4.2 and thiol:protein-disulfide isomerase EC 5.3.4.1 are immunological identical | Homo sapiens | ? | - |
? | |
additional information | thiol:protein-disulfide oxidoreductase EC 1.8.4.2 and thiol:protein-disulfide isomerase EC 5.3.4.1 are immunological identical | Rattus norvegicus | ? | - |
? | |
additional information | thiol:protein-disulfide oxidoreductase EC 1.8.4.2 and thiol:protein-disulfide isomerase EC 5.3.4.1 are immunological identical | Bos taurus | ? | - |
? | |
additional information | enzyme also catalyzes reactivation and folding of protein containing incorrectly paired disulfide bond, e.g.: scrambled ribonuclease | Homo sapiens | ? | - |
? | |
additional information | enzyme also catalyzes reactivation and folding of protein containing incorrectly paired disulfide bond, e.g.: scrambled ribonuclease | Rattus norvegicus | ? | - |
? | |
additional information | enzyme also catalyzes reactivation and folding of protein containing incorrectly paired disulfide bond, e.g.: scrambled ribonuclease | Bos taurus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | the two activities, cleavage and formation of protein-disulfide bonds, present alternate activities of the same enzyme | Homo sapiens |
More | the two activities, cleavage and formation of protein-disulfide bonds, present alternate activities of the same enzyme | Rattus norvegicus |
More | the two activities, cleavage and formation of protein-disulfide bonds, present alternate activities of the same enzyme | Bos taurus |
More | thiol:protein-disulfide oxidoreductase EC 1.8.4.2 and thiol:protein-disulfide isomerase EC 5.3.4.1 are immunological identical | Homo sapiens |
More | thiol:protein-disulfide oxidoreductase EC 1.8.4.2 and thiol:protein-disulfide isomerase EC 5.3.4.1 are immunological identical | Rattus norvegicus |
More | thiol:protein-disulfide oxidoreductase EC 1.8.4.2 and thiol:protein-disulfide isomerase EC 5.3.4.1 are immunological identical | Bos taurus |