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Literature summary for 1.8.4.2 extracted from

  • Kohnert, K.D.; Hahn, H.J.; Zuhlke, H.; Schmidt, S.; Fiedler, H.
    Breakdown of exogenous insulin by Langerhans islets of the pancreas in vitro (1974), Biochim. Biophys. Acta, 338, 68-77.
No PubMed abstract available
Search for more literature for 1.8.4.2

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.014
-
 Insulin
-
 Rattus norvegicus
1.28
-
 GSH
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Rattus norvegicus
-
 Wistar rat
-
Rattus norvegicus
-
 sand rat, i.e. Psammomys obesus
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas pancreatic islets Mus musculus
-
pancreas pancreatic islets Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
9.81
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GSH + protein disulfide
-
 Mus musculus GSSG + protein-dithiol
-
 ?
GSH + protein disulfide
-
 Rattus norvegicus GSSG + protein-dithiol
-
 ?
thioglycolic acid + protein disulfide
-
 Rattus norvegicus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
-
 Rattus norvegicus