Literature summary for 1.8.98.2 extracted from

Biteau, B.; Labarre, J.; Toledano, M.B.
ATP-dependent reduction of cysteine-sulphinic acid by S. cerevisiae sulphiredoxin (2003), Nature, 425, 980-984.

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Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required	Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH	Saccharomyces cerevisiae	sulphiredoxin is important for the antioxidant function of peroxiredoxins, and is likely to be involved in the repair of proteins containing cysteinesulphinic acid modifications, and in signalling pathways involving protein oxidation	peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant	Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH	-	Saccharomyces cerevisiae	peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R	-	?
peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH	sulphiredoxin is important for the antioxidant function of peroxiredoxins, and is likely to be involved in the repair of proteins containing cysteinesulphinic acid modifications, and in signalling pathways involving protein oxidation	Saccharomyces cerevisiae	peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R	-	?

Synonyms

Synonyms	Comment	Organism
sulphiredoxin	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)