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Literature summary for 2.1.1.1 extracted from

  • Scheller, T.; Orgacka, H.; Szumlanski, C.L.; Weinshilboum, R.M.
    Mouse liver nicotinamide N-methyltransferase pharmacogenetics: biochemical properties and variation in activity among inbred strains (1996), Pharmacogenetics, 6, 43-53.
    View publication on PubMed
Search for more literature for 2.1.1.1

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0065
-
 S-adenosyl-L-methionine
-
 Mus musculus
0.37
-
 nicotinamide
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 C57BL/6J
-
Mus musculus C57/BL6J
-
 C57BL/6J
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 activity in male animals of different inbred strains Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + nicotinamide
-
 Mus musculus S-adenosyl-L-homocysteine + 1-methylnicotinamide
-
 ?
S-adenosyl-L-methionine + nicotinamide
-
 Mus musculus C57/BL6J S-adenosyl-L-homocysteine + 1-methylnicotinamide
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
 Mus musculus