Literature summary for 2.1.1.100 extracted from

Kramer, K.; Harrington, E.O.; Lu, Q.; Bellas, R.; Newton, J.; Sheahan, K.L.; Rounds, S.
Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis (2003), Mol. Biol. Cell, 14, 848-857.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Bos taurus	overexpression of the enzyme may protect against endothelial cell apoptosis by enhancing, the carboxyl methylation posttranslational modification, activity, and subsequent intracellular signalling pathway of Ras GTPase	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
endothelial cell	-	Bos taurus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	overexpression of the enzyme may protect against endothelial cell apoptosis by enhancing, the carboxyl methylation posttranslational modification, activity, and subsequent intracellular signalling pathway of Ras GTPase	Bos taurus	?	-	?

Synonyms

Synonyms	Comment	Organism
Icmt	-	Bos taurus
isoprenylcysteine carboxyl methyltransferase	-	Bos taurus

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Release 2023.1 (January 2023)