Crystallization (Comment) | Organism |
---|---|
in complex with amodiaquine, hanging drop vapor diffusion method | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
amodiaquine | i.e. 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol | Plasmodium falciparum | |
Chloroquine | - |
Plasmodium falciparum | |
primaquine | - |
Plasmodium falciparum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + ethanolamine phosphate | Plasmodium falciparum | - |
S-adenosyl-L-homocysteine + N-methylethanolamine phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | Q6T755 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + ethanolamine phosphate | - |
Plasmodium falciparum | S-adenosyl-L-homocysteine + N-methylethanolamine phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phosphoethanolamine methyltransferase | - |
Plasmodium falciparum |
PMT | - |
Plasmodium falciparum |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.46 | - |
pH and temperature not specified in the publication | Plasmodium falciparum | primaquine | |
0.554 | - |
pH and temperature not specified in the publication | Plasmodium falciparum | Chloroquine | |
1.35 | - |
pH and temperature not specified in the publication | Plasmodium falciparum | amodiaquine |