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Literature summary for 2.1.1.107 extracted from

  • Crouzet, J.; Cauchois, L.; Blanche, F.; Debussche, L.; Thibaut, D.; Rouyez, M.C.; Rigault, S.; Mayaux, J.F.; Cameron, B.
    Nucleotide sequence of a Pseudomonas denitrificans 5.4-kilobase DNA fragment containing five cob genes and identification of structural genes encoding S-adenosyl-L-methionine: uroporphyrinogen III methyltransferase and cobyrinic acid a,c-diamide synthase (1990), J. Bacteriol., 172, 5968-5979.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression of 5 open reading frames, codon 1120-1959 (cobA) encodes EC 2.1.1.107 activity Pseudomonas denitrificans (nom. rej.)

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
29200
-
calculated from DNA sequence Pseudomonas denitrificans (nom. rej.)

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 S-adenosyl-L-methionine + uroporphyrinogen III Pseudomonas denitrificans (nom. rej.) involved in biosynthesis of cobalamin 2 S-adenosyl-L-homocysteine + dihydrosirohydrochlorin + 2 H+ product is precorrin-2 ?
2 S-adenosyl-L-methionine + uroporphyrinogen III Pseudomonas denitrificans (nom. rej.) SC510 involved in biosynthesis of cobalamin 2 S-adenosyl-L-homocysteine + dihydrosirohydrochlorin + 2 H+ product is precorrin-2 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas denitrificans (nom. rej.) P21632
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 S-adenosyl-L-methionine + uroporphyrinogen III
-
Pseudomonas denitrificans (nom. rej.) 2 S-adenosyl-L-homocysteine + dihydrosirohydrochlorin + 2 H+ product is precorrin-2 ?
2 S-adenosyl-L-methionine + uroporphyrinogen III involved in biosynthesis of cobalamin Pseudomonas denitrificans (nom. rej.) 2 S-adenosyl-L-homocysteine + dihydrosirohydrochlorin + 2 H+ product is precorrin-2 ?
2 S-adenosyl-L-methionine + uroporphyrinogen III
-
Pseudomonas denitrificans (nom. rej.) SC510 2 S-adenosyl-L-homocysteine + dihydrosirohydrochlorin + 2 H+ product is precorrin-2 ?
2 S-adenosyl-L-methionine + uroporphyrinogen III involved in biosynthesis of cobalamin Pseudomonas denitrificans (nom. rej.) SC510 2 S-adenosyl-L-homocysteine + dihydrosirohydrochlorin + 2 H+ product is precorrin-2 ?