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Literature summary for 2.1.1.131 extracted from

  • Shearer, N.; Hinsley, A.P.; Van Spanning, R.J.; Spiro, S.
    Anaerobic growth of Paracoccus denitrificans requires cobalamin: characterization of cobK and cobJ genes (1999), J. Bacteriol., 181, 6907-6913.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene cobJ, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in a pleiotropic mutant strain high has a severe defect in anaerobic growth, the phenotype can be reversed by cobalamin and complemented by expression of genes of the cobalamin biosynthetic pathway, overview Paracoccus denitrificans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Paracoccus denitrificans Paracoccus denitrificans uses the aerobic pathway for cobalamin biosynthesis ?
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?
S-Adenosyl-L-methionine + precorrin-3B Paracoccus denitrificans enzyme is involved in the aerobic cobalamin biosynthesis S-Adenosyl-L-homocysteine + precorrin-4
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?

Organism

Organism UniProt Comment Textmining
Paracoccus denitrificans Q9R9K1 gene cobJ
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information Paracoccus denitrificans uses the aerobic pathway for cobalamin biosynthesis Paracoccus denitrificans ?
-
?
S-Adenosyl-L-methionine + precorrin-3B
-
Paracoccus denitrificans S-Adenosyl-L-homocysteine + precorrin-4
-
?
S-Adenosyl-L-methionine + precorrin-3B enzyme is involved in the aerobic cobalamin biosynthesis Paracoccus denitrificans S-Adenosyl-L-homocysteine + precorrin-4
-
?

Synonyms

Synonyms Comment Organism
Precorrin-3B methyltransferase
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Paracoccus denitrificans