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Literature summary for 2.1.1.131 extracted from

  • Roessner, C.A.; Huang, K.X.; Warren, M.J.; Raux, E.; Scott, A.I.
    Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. Shermanii) (2002), Microbiology, 148, 1845-1853.
    View publication on PubMed
Search for more literature for 2.1.1.131

Cloned(Commentary)

Cloned (Comment) Organism
gene cbiEGH, the gene cbiH of Propionibacterium freudenreichii is organized in a single ORF with genes cbiE and cbiG, DNA and amino acid sequence determination and analysis, genetic organization, co-overexpression of enzymes and reconstruction of the anaerobic cobalamin biosynthetic pathway in Escherichia coli in a construct comprising several genes, overview Propionibacterium freudenreichii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
91400
-
 x * 91400, about, cbiEGH protein, amino acid sequence calculation and SDS-PAGE Propionibacterium freudenreichii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Pseudomonas denitrificans (nom. rej.) the organism performs the aerobic cobalamin biosynthesis variant ?
-
 ?
additional information Propionibacterium freudenreichii the organism performs the anaerobic cobalamin biosynthesis variant, the gene cbiH of Propionibacterium freudenreichii is organized in a single ORF with genes cbiE and cbiG, overview ?
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-3B Pseudomonas denitrificans (nom. rej.) enzyme is involved in the anaerobic cobalamin biosynthesis, pathway overview S-adenosyl-L-homocysteine + cobalt-precorrin-4
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-3B Propionibacterium freudenreichii enzyme is involved in the anaerobic cobalamin biosynthesis, pathway overview S-adenosyl-L-homocysteine + cobalt-precorrin-4
-
 ?

Organism

Organism UniProt Comment Textmining
Propionibacterium freudenreichii
-
 i.e. Propionibacterium shermanii, gene cbiH
-
Pseudomonas denitrificans (nom. rej.)
-
 gene cobJ
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the organism performs the aerobic cobalamin biosynthesis variant Pseudomonas denitrificans (nom. rej.) ?
-
 ?
additional information the organism performs the anaerobic cobalamin biosynthesis variant, the gene cbiH of Propionibacterium freudenreichii is organized in a single ORF with genes cbiE and cbiG, overview Propionibacterium freudenreichii ?
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-3 C-17 methylation and ring contraction Pseudomonas denitrificans (nom. rej.) S-adenosyl-L-homocysteine + cobalt-precorrin-4
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-3 C-17 methylation and ring contraction Propionibacterium freudenreichii S-adenosyl-L-homocysteine + cobalt-precorrin-4
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-3B enzyme is involved in the anaerobic cobalamin biosynthesis, pathway overview Pseudomonas denitrificans (nom. rej.) S-adenosyl-L-homocysteine + cobalt-precorrin-4
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-3B enzyme is involved in the anaerobic cobalamin biosynthesis, pathway overview Propionibacterium freudenreichii S-adenosyl-L-homocysteine + cobalt-precorrin-4
-
 ?

Subunits

Subunits Comment Organism
? x * 91400, about, cbiEGH protein, amino acid sequence calculation and SDS-PAGE Propionibacterium freudenreichii