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Literature summary for 2.1.1.137 extracted from

  • Fujihara, J.; Kunito, T.; Agusa, T.; Yasuda, T.; Iida, R.; Fujii, Y.; Takeshita, H.
    Population differences in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene polymorphism detected by using genotyping method (2007), Toxicol. Appl. Pharmacol., 225, 251-254.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, genotyping with method development and optimization, overview Homo sapiens

Protein Variants

Protein Variants Comment Organism
M287T genotype distribution and allele frequencies of M287T in Ovambo, Turkish, Mongolian, Korean, and Japanese populations , the mutation frequencies in Asian populations are relatively lower than those of African and Caucasian populations, the frequencies of mutation in the Mongolian, Korean, and Japanese populations, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + arsenite Homo sapiens
-
S-adenosyl-L-homocysteine + methylarsonate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9HBK9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + arsenite
-
Homo sapiens S-adenosyl-L-homocysteine + methylarsonate
-
?

Synonyms

Synonyms Comment Organism
arsenic (+3 oxidation state) methyltransferase
-
Homo sapiens
AS3MT
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
Homo sapiens