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Literature summary for 2.1.1.137 extracted from

  • Tokumoto, M.; Kutsukake, N.; Yamanishi, E.; Katsuta, D.; Anan, Y.; Ogra, Y.
    Arsenic (+3 oxidation state) methyltransferase is a specific but replaceable factor against arsenic toxicity (2014), Toxicol. Rep., 1, 589-595.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.137

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli DH10B cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + arsenite Homo sapiens
-
 S-adenosyl-L-homocysteine + methylarsonate
-
 ?
S-adenosyl-L-methionine + methylarsonite Homo sapiens
-
 S-adenosyl-L-homocysteine + dimethylarsinate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9HBK9
-
-

Purification (Commentary)

Purification (Comment) Organism
nickel affinity His GraviTrap column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme does not methylate selenium and tellurium Homo sapiens ?
-
 ?
S-adenosyl-L-methionine + arsenite
-
 Homo sapiens S-adenosyl-L-homocysteine + methylarsonate
-
 ?
S-adenosyl-L-methionine + methylarsonite
-
 Homo sapiens S-adenosyl-L-homocysteine + dimethylarsinate
-
 ?

Synonyms

Synonyms Comment Organism
arsenic (+3 oxidation state) methyltransferase
-
 Homo sapiens
AS3MT
-
 Homo sapiens