Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.14 extracted from

  • Taylor, R.T.; Weissbach, H.
    N5-Methyltetrahydrofolate-homocysteine methyltransferases (1973), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 9, 121-165.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
Auxenochlorella pyrenoidosa
EDTA
-
Escherichia coli
EDTA
-
Klebsiella aerogenes
EDTA
-
Neurospora crassa
EDTA
-
Saccharomyces cerevisiae
EDTA
-
Salmonella enterica subsp. enterica serovar Typhimurium

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ can replace Mg2+ Salmonella enterica subsp. enterica serovar Typhimurium
Ca2+ can replace Mg2+ Neurospora crassa
Ca2+ can replace Mg2+ Klebsiella aerogenes
Ca2+ can replace Mg2+ Auxenochlorella pyrenoidosa
Mg2+ stimulates Salmonella enterica subsp. enterica serovar Typhimurium
Mg2+ stimulates Escherichia coli
Mg2+ stimulates Neurospora crassa
Mg2+ stimulates Klebsiella aerogenes
Mg2+ stimulates Auxenochlorella pyrenoidosa
Mg2+ no stimulation Saccharomyces cerevisiae
phosphate
-
Salmonella enterica subsp. enterica serovar Typhimurium
phosphate
-
Escherichia coli
phosphate
-
Saccharomyces cerevisiae
phosphate
-
Neurospora crassa
phosphate
-
Klebsiella aerogenes
phosphate
-
Auxenochlorella pyrenoidosa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50800
-
x * 50800, equilibrium sedimentation of carboxymethylated enzyme in 5 M guanidine-HCl Escherichia coli
75000
-
gel filtration, sedimentation data Saccharomyces cerevisiae
84000
-
equilibrium ultracentrifugation Escherichia coli

Organism

Organism UniProt Comment Textmining
Auxenochlorella pyrenoidosa
-
-
-
Escherichia coli
-
-
-
Klebsiella aerogenes
-
-
-
Neurospora crassa
-
-
-
Saccharomyces cerevisiae
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information monoglutamate analog not used Salmonella enterica subsp. enterica serovar Typhimurium ?
-
?
additional information monoglutamate analog not used Escherichia coli ?
-
?
additional information monoglutamate analog not used Saccharomyces cerevisiae ?
-
?
additional information monoglutamate analog not used Neurospora crassa ?
-
?
additional information monoglutamate analog not used Klebsiella aerogenes ?
-
?
additional information monoglutamate analog not used Auxenochlorella pyrenoidosa ?
-
?

Subunits

Subunits Comment Organism
? x * 50800, equilibrium sedimentation of carboxymethylated enzyme in 5 M guanidine-HCl Escherichia coli

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.6 7.6
-
Saccharomyces cerevisiae
7.5 7.8
-
Escherichia coli

Cofactor

Cofactor Comment Organism Structure
additional information vitamin-B12 independent enzyme Salmonella enterica subsp. enterica serovar Typhimurium
additional information vitamin-B12 independent enzyme Escherichia coli
additional information vitamin-B12 independent enzyme Saccharomyces cerevisiae
additional information vitamin-B12 independent enzyme Neurospora crassa
additional information vitamin-B12 independent enzyme Klebsiella aerogenes
additional information vitamin-B12 independent enzyme Auxenochlorella pyrenoidosa