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Literature summary for 2.1.1.148 extracted from

  • Chernyshev, A.; Fleischmann, T.; Koehn, E.M.; Lesley, S.A.; Kohen, A.
    The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS) (2007), Chem. Commun. (Camb. ), 27, 2861-2863.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.148

Application

Application Comment Organism
medicine antibiotic target Thermotoga maritima

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5,10-methylenetetrahydrofolate + dUMP + FADH2 + O2 Thermotoga maritima
-
 dTMP + tetrahydrofolate + FAD + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Thermotoga maritima
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + dUMP + FADH2 + O2
-
 Thermotoga maritima dTMP + tetrahydrofolate + FAD + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
FDTS
-
 Thermotoga maritima
flavin dependent thymidylate synthase
-
 Thermotoga maritima

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Thermotoga maritima
NADPH
-
 Thermotoga maritima