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Literature summary for 2.1.1.157 extracted from

  • Lai, M.C.; Wang, C.C.; Chuang, M.J.; Wu, Y.C.; Lee, Y.C.
    Effects of substrate and potassium on the betaine-synthesizing enzyme glycine sarcosine dimethylglycine N-methyltransferase from a halophilic methanoarchaeon Methanohalophilus portucalensis (2006), Res. Microbiol., 157, 948-955.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
K+ highest activity at 0.8 M K+ Methanohalophilus portucalensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + N,N-dimethylglycine Methanohalophilus portucalensis synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
-
?
S-adenosyl-L-methionine + N,N-dimethylglycine Methanohalophilus portucalensis FDF1 synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
-
?
S-adenosyl-L-methionine + N-methylglycine Methanohalophilus portucalensis synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
?
S-adenosyl-L-methionine + N-methylglycine Methanohalophilus portucalensis FDF1 synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
?

Organism

Organism UniProt Comment Textmining
Methanohalophilus portucalensis
-
one peak showing SDMT activity eluted from chromatofocusing column
-
Methanohalophilus portucalensis FDF1
-
one peak showing SDMT activity eluted from chromatofocusing column
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + N,N-dimethylglycine synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine Methanohalophilus portucalensis S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
-
?
S-adenosyl-L-methionine + N,N-dimethylglycine synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine Methanohalophilus portucalensis FDF1 S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
-
?
S-adenosyl-L-methionine + N-methylglycine synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine Methanohalophilus portucalensis S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
?
S-adenosyl-L-methionine + N-methylglycine synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine Methanohalophilus portucalensis FDF1 S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
?

Synonyms

Synonyms Comment Organism
SDMT
-
Methanohalophilus portucalensis