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Literature summary for 2.1.1.159 extracted from

  • Uefuji, H.; Tatsumi, Y.; Morimoto, M.; Kaothien-Nakayama, P.; Ogita, S.; Sano, H.
    Caffeine production in tobacco plants by simultaneous expression of three coffee N-methyltranferases and its potential as a pest repellant (2005), Plant Mol. Biol., 59, 221-227.
    View publication on PubMed
Search for more literature for 2.1.1.159

Application

Application Comment Organism
agriculture expression of the caffeine biosynthesis enzymes in transgenic crop plants may protect against the crop damaging larvae of pests Coffea arabica

Cloned(Commentary)

Cloned (Comment) Organism
isozyme MXMT1, functional expression in transgenic Nicotiana tabacum plant leaves Coffea arabica

Protein Variants

Protein Variants Comment Organism
additional information transgenic Nicotiana tabacum plant leaves expressing all three enzymes required for the biosynthesis of caffeine are no longer eaten by the tobacco cutworm caterpillars, Spodoptera litura, overview Coffea arabica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + 7-methylxanthine Coffea arabica
-
 S-adenosyl-L-homocysteine + 3,7-dimethylxanthine i.e. theobromine ir
S-adenosyl-L-methionine + paraxanthine Coffea arabica
-
 S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir

Organism

Organism UniProt Comment Textmining
Coffea arabica Q9AVJ9 isozyme MXMT1; isozyme MXMT1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 7-methylxanthine
-
 Coffea arabica S-adenosyl-L-homocysteine + 3,7-dimethylxanthine i.e. theobromine ir
S-adenosyl-L-methionine + paraxanthine
-
 Coffea arabica S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir

Synonyms

Synonyms Comment Organism
MXMT1
-
 Coffea arabica