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Literature summary for 2.1.1.163 extracted from

  • Lee, P.T.; Hsu, A.Y.; Ha, H.T.; Clarke, C.F.
    A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene (1997), J. Bacteriol., 179, 1748-1754.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.163

Protein Variants

Protein Variants Comment Organism
G142D mutant accumulates 2-octaprenyl-6-methoxy-1,4-benzoquinone and demethylmenaquinone as predominant intermediates Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A887
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-methoxy-2-octaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine
-
 Escherichia coli 6-methoxy-3-methyl-2-octaprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine
-
 ?
demethylmenaquinol + S-adenosyl-L-methionine
-
 Escherichia coli menaquinol + S-adenosyl-L-homocysteine
-
 ?

Synonyms

Synonyms Comment Organism
UbiE
-
 Escherichia coli

General Information

General Information Comment Organism
physiological function strains containing either a disruption or point mutation G142D in ubiE accumulate 2-octaprenyl-6-methoxy-1,4-benzoquinone and demethylmenaquinone as predominant intermediates. Disruption mutants show defects in growth on succinate. The UbiE polypeptide is required for the C methylation reactions in both ubiquinone and menaquinone biosynthesis Escherichia coli