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Literature summary for 2.1.1.192 extracted from

  • Grove, T.; Livada, J.; Schwalm, E.; Green, M.; Booker, S.; Silakov, A.
    A substrate radical intermediate in catalysis by the antibiotic resistance protein Cfr (2013), Nat. Chem. Biol., 9, 422-427.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + adenine2503 in 23S rRNA Staphylococcus aureus the enzyme methylates C8 in adenine2503 in 23S rRNA S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2-methyladenine2503 in 23S rRNA
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Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + adenine2503 in 23S rRNA the enzyme methylates C8 in adenine2503 in 23S rRNA Staphylococcus aureus S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2-methyladenine2503 in 23S rRNA
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Synonyms

Synonyms Comment Organism
Cfr
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Staphylococcus aureus