Literature summary for 2.1.1.195 extracted from

Roessner, C.A.; Williams, H.J.; Scott, A.I.
Genetically engineered production of 1-desmethylcobyrinic acid, 1-desmethylcobyrinic acid a,c-diamide, and cobyrinic acid a,c-diamide in Escherichia coli implies a role for CbiD in C-1 methylation in the anaerobic pathway to cobalamin (2005), J. Biol. Chem., 280, 16748-16753.

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Application

Application	Comment	Organism
synthesis	coexpression of the cobA gene from Propionibacterium freudenreichii and the cbiA, -C, -D, -E, -T, -F, -G, -H, -J, -K, -L, and -P genes from Salmonella enterica serovar typhimurium in Escherichia coli result in the production of cobyrinic acid a,c-diamide. A cbiD deletion mutant of this strain produces 1-desmethylcobyrinic acid a,c-diamide, indicating that CbiD is involved in C-1 methylation in the anaerobic pathway to cobalamin	Salmonella enterica

Organism

Organism	UniProt	Comment	Textmining
Salmonella enterica	Q05628	-	-

Synonyms

Synonyms	Comment	Organism
CbiD	-	Salmonella enterica

General Information

General Information	Comment	Organism
physiological function	CbiD is involved in C-1 methylation in the anaerobic pathway to cobalamin	Salmonella enterica

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Release 2023.1 (January 2023)