Literature summary for 2.1.1.209 extracted from

Mosbacher, T.G.; Bechthold, A.; Schulz, G.E.
Crystal structure of the avilamycin resistance-conferring methyltransferase AviRa from Streptomyces viridochromogenes (2003), J. Mol. Biol., 329, 147-157.

Search for more literature for 2.1.1.209

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Streptomyces viridochromogenes

Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging-drop vapour-diffusion method at 20°C. 1.5 A crystal structure	Streptomyces viridochromogenes

Protein Variants

Protein Variants	Comment	Organism
I11SeMet/L239SeMet	as active as wild-type enzyme	Streptomyces viridochromogenes
I11SeMet/L246SeMet	as active as wild-type enzyme	Streptomyces viridochromogenes
L173SeMet/L239SeMet	as active as wild-type enzyme	Streptomyces viridochromogenes
L239SeMet/L246SeMet	as active as wild-type enzyme	Streptomyces viridochromogenes

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + guanine2535 in 23S rRNA	Streptomyces viridochromogenes	confers resistance to antibiotic avilamycin	S-adenosyl-L-homocysteine + N1-methylguanine2535 in 23S rRNA	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces viridochromogenes	Q9F5K5	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + guanine2535 in 23S rRNA	confers resistance to antibiotic avilamycin	Streptomyces viridochromogenes	S-adenosyl-L-homocysteine + N1-methylguanine2535 in 23S rRNA	-	?

Synonyms

Synonyms	Comment	Organism
AviRa	-	Streptomyces viridochromogenes

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Release 2023.1 (January 2023)