Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + uridine44 in tRNASer | Saccharomyces cerevisiae | 2'-O-methylation of uridine44 contributes to stability of tRNASer(CGA) | S-adenosyl-L-homocysteine + 2'-O-methyluridine44 in tRNASer | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | Q02648 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + uridine44 in tRNASer | - |
Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + 2'-O-methyluridine44 in tRNASer | - |
? | |
S-adenosyl-L-methionine + uridine44 in tRNASer | 2'-O-methylation of uridine44 contributes to stability of tRNASer(CGA) | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + 2'-O-methyluridine44 in tRNASer | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TRM44 | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
malfunction | trm44-DELTA strain lacks 2'-O-methyltransferase activity and has undetectable levels of Um44 in its tRNASer. Although trm44-DELTA mutants have no detectable growth defect, TRM44 is required for survival at 33°C in a tan1-DELTA mutant strain, which lacks ac4C12 in tRNASer and tRNALeu | Saccharomyces cerevisiae |