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Literature summary for 2.1.1.219 extracted from
- Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase (2010), Nucleic Acids Res., 38, 6206-6218.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| crystal structure TrmI in complex with SAH is determined in two different space groups at 2.6 and 2.05 A resolution, and in complex with S-adenosyl-L-methionine (SAM) at 1.6 A resolution | Pyrococcus abyssi |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pyrococcus abyssi | Q9V1J7 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pyrococcus abyssi |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2 S-adenosyl-L-methionine + adenine57/adenine58 in tRNAAsp | the presence of adenine at position 59 in Pyrococcus abyssi tRNA(Asp) is important for the multi-site specificity of the archaeal enzyme at both positions 57 and 58 in tRNAAsp. His78 near the active site is important for efficient catalysis | Pyrococcus abyssi | 2 S-adenosyl-L-homocysteine + N1-methyladenine57/N1-methyladenine58 in tRNAAsp | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TrmI | - |
Pyrococcus abyssi |
| tRNA m1A57/58 methyltransferase | - |
Pyrococcus abyssi |
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Release 2023.1 (January 2023)
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