General Stability | Organism |
---|---|
stable on freezing and thawing | Gallus gallus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.09 | - |
S-adenosyl-L-methionine | - |
Gallus gallus | |
4 | - |
carnosine | - |
Gallus gallus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Gallus gallus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | inhibitory, reversible by addition of EDTA | Gallus gallus | |
Mn2+ | inhibitory, reversible by addition of EDTA | Gallus gallus | |
Zn2+ | inhibitory, reversible by addition of EDTA | Gallus gallus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + carnosine | Gallus gallus | biosynthesis of anserine | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | Cavia porcellus | biosynthesis of anserine | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | Rattus norvegicus | biosynthesis of anserine | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | Oryctolagus cuniculus | biosynthesis of anserine | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | Felis catus | biosynthesis of anserine | S-adenosyl-L-homocysteine + anserine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Felis catus | - |
- |
- |
Gallus gallus | - |
White Rock chick | - |
Oryctolagus cuniculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Gallus gallus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | low activity | Gallus gallus | - |
brain | low activity | Cavia porcellus | - |
brain | low activity | Rattus norvegicus | - |
heart | low activity | Cavia porcellus | - |
heart | low activity | Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
kidney | much lower activity than in muscle | Gallus gallus | - |
kidney | much lower activity than in muscle | Cavia porcellus | - |
kidney | much lower activity than in muscle | Oryctolagus cuniculus | - |
kidney | much lower activity than in muscle | Felis catus | - |
kidney | about the same activity as in muscle | Gallus gallus | - |
liver | same activity than in muscle | Gallus gallus | - |
liver | 20% of activity in muscle | Rattus norvegicus | - |
lung | - |
Cavia porcellus | - |
lung | - |
Rattus norvegicus | - |
muscle | - |
Gallus gallus | - |
muscle | - |
Cavia porcellus | - |
muscle | - |
Rattus norvegicus | - |
muscle | - |
Oryctolagus cuniculus | - |
muscle | - |
Felis catus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0005 | - |
purified enzyme | Gallus gallus |
Storage Stability | Organism |
---|---|
-20°C, very stable | Gallus gallus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + carnosine | - |
Gallus gallus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | - |
Cavia porcellus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | - |
Oryctolagus cuniculus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | - |
Felis catus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | biosynthesis of anserine | Gallus gallus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | biosynthesis of anserine | Cavia porcellus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | biosynthesis of anserine | Rattus norvegicus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | biosynthesis of anserine | Oryctolagus cuniculus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + carnosine | biosynthesis of anserine | Felis catus | S-adenosyl-L-homocysteine + anserine | - |
? | |
S-adenosyl-L-methionine + homocarnosine | - |
Cavia porcellus | S-adenosyl-L-homocysteine + homoanserine | - |
? | |
S-adenosyl-L-methionine + homocarnosine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + homoanserine | - |
? | |
S-adenosyl-L-methionine + L-histidine | - |
Cavia porcellus | S-adenosyl-L-homocysteine + Ntau-methyl-L-histidine | - |
? | |
S-adenosyl-L-methionine + L-histidine | - |
Oryctolagus cuniculus | S-adenosyl-L-homocysteine + Ntau-methyl-L-histidine | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
no loss of activity within 5 min in presence of carnosine | Gallus gallus |
50 | - |
30% loss of activity when heated for 10 min in presence of carnosine, 70% loss of activity within 3 min in absence of carnosine | Gallus gallus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8.5 | - |
Gallus gallus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 9 | - |
Gallus gallus |