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Literature summary for 2.1.1.229 extracted from

  • Jablonowski, D.; Zink, S.; Mehlgarten, C.; Daum, G.; Schaffrath, R.
    tRNAGlu wobble uridine methylation by Trm9 identifies Elongator's key role for zymocin-induced cell death in yeast (2006), Mol. Microbiol., 59, 677-688.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P49957
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + carboxymethyluridine34 in tRNA Trm9 methylates the uridine wobble base of tRNAGlU(UUC) Saccharomyces cerevisiae S-adenosyl-L-homocysteine + 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA
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Synonyms

Synonyms Comment Organism
Trm9
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Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction trm9DELTA cells lacking a tRNA methylase specific for wobble uridine (U34) residues survive zymocin Saccharomyces cerevisiae