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Literature summary for 2.1.1.249 extracted from

  • Veit, K.; Ehlers, C.; Schmitz, R.
    Effects of nitrogen and carbon sources on transcription of soluble methyltransferases in Methanosarcina mazei strain Gö1 (2005), J. Bacteriol., 187, 6147-6154.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.249

Cloned(Commentary)

Cloned (Comment) Organism
genes mtbB1 and mtbB2C2, operon encoding DMA methylamine methyltransferase, quantitative RT-PCR expression analysis, comparison with other methylamine methyltransferases, overview. Transcriptional regulation of genes encoding methylamine methyltransferases in cells growing on trimethylamine or methanol in the presence of ammonium, overview Methanosarcina mazei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dimethylamine + a [Co(I) dimethylamine-specific corrinoid protein] Methanosarcina mazei
-
 a [methyl-Co(III) dimethylamine-specific corrinoid protein] + methylamine
-
 ?
dimethylamine + a [Co(I) dimethylamine-specific corrinoid protein] Methanosarcina mazei Goe1
-
 a [methyl-Co(III) dimethylamine-specific corrinoid protein] + methylamine
-
 ?

Organism

Organism UniProt Comment Textmining
Methanosarcina mazei
-
 DSM 3647, genes mtbB1 and mtbB2C2
-
Methanosarcina mazei Goe1
-
 DSM 3647, genes mtbB1 and mtbB2C2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dimethylamine + a [Co(I) dimethylamine-specific corrinoid protein]
-
 Methanosarcina mazei a [methyl-Co(III) dimethylamine-specific corrinoid protein] + methylamine
-
 ?
dimethylamine + a [Co(I) dimethylamine-specific corrinoid protein]
-
 Methanosarcina mazei Goe1 a [methyl-Co(III) dimethylamine-specific corrinoid protein] + methylamine
-
 ?

General Information

General Information Comment Organism
metabolism when growing on trimethylamine, nitrogen fixation does not occur in the cells, indicating that ammonium released during trimethylamine degradation is sufficient to serve as a nitrogen source and represses nif gene induction, transcriptional regulation of soluble methyltransferases, which catalyze the initial step of methylamine consumption by methanogenesis, in response to different carbon and nitrogen sources, overview. Transcription of the operon encoding DMA methyltransferase is not regulated in response to the nitrogen source. Regulation of soluble methyltransferases in response to different nitrogen and carbon sources, overview Methanosarcina mazei