Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ag2+ | - |
Rattus norvegicus | |
Co2+ | - |
Rattus norvegicus | |
Cu2+ | 0.01 M, strong | Rattus norvegicus | |
Fe2+ | - |
Rattus norvegicus | |
glycine betaine | 0.1 M | Rattus norvegicus | |
Hg2+ | 0.01 M, strong | Rattus norvegicus | |
hydroxylamine | 0.01 M | Rattus norvegicus | |
K+ | - |
Rattus norvegicus | |
Mn2+ | - |
Rattus norvegicus | |
additional information | no inhibition by dimethylthetin, sulfocholine (up to 0.1 M), mercaptoethanol, cysteine, Na2SO4, Li+, Cs+, Ca2+, Mg2+, NaN3, NaCN, NaF, EDTA, semicarbazide, iodoacetate | Rattus norvegicus | |
phenylhydrazine | 0.01 M | Rattus norvegicus | |
Rb+ | - |
Rattus norvegicus | |
Sodium mercaptoacetate | - |
Rattus norvegicus | |
Zn2+ | 0.01 M, strong | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no activation by metal ions | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dimethylthetin + L-homocysteine | Rattus norvegicus | - |
S-methylthioglycolate + L-methionine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
dimethylsulfonioacetate + L-homocysteine = (methylsulfanyl)acetate + L-methionine | mechanism | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dimethylthetin + L-homocysteine | - |
Rattus norvegicus | S-methylthioglycolate + L-methionine | - |
? | |
dimethylthetin + L-homocysteine | i.e. dimethylsulfonioacetate, specific for L-homocysteine | Rattus norvegicus | S-methylthioglycolate + L-methionine | i.e. methylthioacetate | ? | |
additional information | methyl group donors are ethylmethylthetin, dimethyl-alpha- and dimethyl-beta-propiothetin, ethylmethyl-beta-propiothetin, dimethyl-gamma-butyrothetin, methionine methylsulfonium, trimethylsulfonium, ethyldimethylsulfonium or butyldimethylsulfonium, no acceptors are cysteamine, 2-mercaptoethanol, DL-homocystine, sodium mercaptoacetate | Rattus norvegicus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Rattus norvegicus |