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Literature summary for 2.1.1.319 extracted from

  • Stouth, D.W.; Manta, A.; Ljubicic, V.
    Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity (2018), Am. J. Physiol. Cell Physiol., 314, C177-C190 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.319

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol PRMT1 enzyme localization is concentrated in the cytosolic, membrane, and myonuclear compartments of mature myofibers Mus musculus 5829
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cytosol PRMT4 enzyme localization is concentrated in the cytosolic, membrane, and myonuclear compartments of mature myofibers Mus musculus 5829
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membrane PRMT1 enzyme localization is concentrated in the cytosolic, membrane, and myonuclear compartments of mature myofibers Mus musculus 16020
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membrane PRMT4 enzyme localization is concentrated in the cytosolic, membrane, and myonuclear compartments of mature myofibers Mus musculus 16020
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Organism

Organism UniProt Comment Textmining
Mus musculus Q9JIF0
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Mus musculus Q9WVG6
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Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle PRMT1 enzyme localization is concentrated in the cytosolic, membrane, and myonuclear compartments of mature myofibers Mus musculus
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skeletal muscle PRMT4 enzyme localization is concentrated in the cytosolic, membrane, and myonuclear compartments of mature myofibers Mus musculus
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Synonyms

Synonyms Comment Organism
CARM1
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 Mus musculus
PRMT1
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 Mus musculus
PRMT4
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 Mus musculus
protein arginine methyltransferase 1
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 Mus musculus
protein arginine methyltransferase 4
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 Mus musculus

Expression

Organism Comment Expression
Mus musculus PRMT1 mRNA content in the denervated soleus muscle decreases by 32% and 37% as compared with the control muscle after 6 and 12 h, respectively down
Mus musculus relative to the control muscle, PRMT4 mRNA expression levels in the denervated soleus muscle is decreased by 31% after 12 h down
Mus musculus following 72 h and 168 h of denervation, PRMT1 protein content increases 3.6-5fold up
Mus musculus PRMT4 mRNA content increases 2.3fold or 1.7fold in the denervated muscle compared with the control muscle after 72 and 168 h of denervation, respectively up

General Information

General Information Comment Organism
physiological function PRMT1 expression, localization, and activity are altered following denervation-induced inactivity. Evidence from correlation, colocalization, and interaction analyses strongly support the existence of a novel, functional PRMT1-AMPKPGC-1alpha axis in skeletal muscle that is active during phenotypic remodeling elicited by denervation-evoked atrophy Mus musculus
physiological function PRMT4 expression, localization, and activity are altered following denervation-induced inactivity Mus musculus