Application | Comment | Organism |
---|---|---|
analysis | dissociation of tRNA from the tRNA-enzyme complex after the methyl-transfer reaction is caused by the dissociation of enzyme subunits | Thermus thermophilus |
Protein Variants | Comment | Organism |
---|---|---|
R14M | dissociation of subunits consistent with that from the wild-type enzyme | Thermus thermophilus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermus thermophilus | - |
- |
- |
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + tRNA | - |
Thermus thermophilus | S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanine | - |
? | |
S-adenosyl-L-methionine + tRNA | - |
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanine | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | in the absence of S-adenosyl-L-methionine or S-adenosyl-L-homocysteine | Thermus thermophilus |
monomer | addition of S-adenosyl-L-homocysteine causes the dissociation of subunits and gives rise to a monomer structure | Thermus thermophilus |
tetramer | in the presence of S-adenosyl-L-methionine | Thermus thermophilus |
Synonyms | Comment | Organism |
---|---|---|
transfer RNA (Gm18) methyltransferase | - |
Thermus thermophilus |
TrmH | - |
Thermus thermophilus |
tRNA (Gm18) methyltransferase | - |
Thermus thermophilus |