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Literature summary for 2.1.1.37 extracted from
- Expression of rat DNA (cytosine-5) methyltransferase (DNA MTase) in rodent trophoblast giant cells: molecular cloning and characterization of rat DNA MTase (1998), Biochem. Biophys. Res. Commun., 253, 495-501.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | methylation of genomic DNA is involved in the basic mechanism of gene inactivation, chromatin organization, X-chromosome inactivation, and genomic imprinting | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | Q9Z330 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| placenta | the enzyme is highly expressed in placenta during mid-to late-pregnancy | Rattus norvegicus | - |
| Rcho-1 cell | the enzyme is regulated at the posttranscriptional level in terminally differentiating Rcho-1 cell | Rattus norvegicus | - |
| trophoblast | giant cell | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | methylation of genomic DNA is involved in the basic mechanism of gene inactivation, chromatin organization, X-chromosome inactivation, and genomic imprinting | Rattus norvegicus | ? | - |
? | |
| S-adenosyl-L-methionine + DNA | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine | - |
? | |
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