Protein Variants | Comment | Organism |
---|---|---|
additional information | CG methylation is lost in a drm1/2/cmt3 mutant, and non-CG methylation is almost completely eliminated in a met1 mutant. Exceptional maintenance of methylation at a CCmTGG site in some epigenetic mutants, overview | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + S-adenosyl-L-methionine | Arabidopsis thaliana | - |
DNA containing 5-methylcytosine + S-adenosyl-L-homocysteine | - |
? | |
additional information | Arabidopsis thaliana | DNA fragment RPS belongs to a group of middle repetitive, dispersed and hypermethylated homologues. Repetitiveness, however, is not a prerequisite for hypermethylation, as RPS transgenes are efficient methylation targets in Arabidopsis, which lacks any significant RPS homology | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q94F88 | - |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
CG methylation, CNG methylation, and CNN methylation rates, overview | Arabidopsis thaliana |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + S-adenosyl-L-methionine | - |
Arabidopsis thaliana | DNA containing 5-methylcytosine + S-adenosyl-L-homocysteine | - |
? | |
DNA fragment RPS + S-adenosyl-L-methionine | RPS is a repetitive hypermethylated DNA fragment from Petunia hybrida. CG methylation, CNG methylation, and CNN methylation. MET1 maintains CG methylation, and DRM1/2 and CMT3 act redundantly to enforce non-CG methylation, unusual cooperative activity of all three DNA methyltransferases is therefore required for maintenance of both CG and non-CG methylation in RPS. Arabidopsis thaliana does not contain any RPS homologues. Methylation at the CCmTGG site also requires DRM1/2, MET1, and, to a lesser extent, CMT3 | Arabidopsis thaliana | DNA fragment RPS containing 5-methylcytosine + S-adenosyl-L-homocysteine | - |
? | |
additional information | DNA fragment RPS belongs to a group of middle repetitive, dispersed and hypermethylated homologues. Repetitiveness, however, is not a prerequisite for hypermethylation, as RPS transgenes are efficient methylation targets in Arabidopsis, which lacks any significant RPS homology | Arabidopsis thaliana | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CMT3 | - |
Arabidopsis thaliana |
DRM1/2 | - |
Arabidopsis thaliana |
MET1 | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-L-methionine | - |
Arabidopsis thaliana |