Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-fluoropyrimidine-2,4(1H,3H)-dione | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,10-methylenetetrahydrofolate + dUMP | - |
Homo sapiens | dihydrofolate + dTMP | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
N5,N10-methylenetetrahydrofolate | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | there is an approximately 2fold inverse relationship between thymidylate synthase expression and response to 5-fluoruracil | down |