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Literature summary for 2.1.1.5 extracted from

  • Finkelstein, J.D.; Kyle, W.E.; Harris, B.J.
    Methionine metabolism in mammals: regulatory effects of S-adenosylhomocysteine (1974), Arch. Biochem. Biophys., 165, 774-779.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
S-adenosyl-L-homocysteine non-linear/competitive to homocysteine, mixed/non-competitive to betaine Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
betaine + L-homocysteine = dimethylglycine + L-methionine ordered bi-bi mechanism with homocysteine the first substrate to be added and methionine the last product released Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-