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Literature summary for 2.1.1.5 extracted from

  • Pillai, P.B.; Fanatico, A.C.; Beers, K.W.; Blair, M.E.; Emmert, J.L.
    Homocysteine remethylation in young broilers fed varying levels of methionine, choline, and betaine (2006), Poult. Sci., 85, 90-95.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
betaine only slightly increased homocysteine remethylation in response to addition of betaine to diets containing 0.07 and 0.24% supplemental methionine Gallus gallus
additional information dietary methionine level does not significantly affect BHMT-dependent homocysteine remethylation or the relative proportion of homocysteine that is remethylated by BHMT, also choline appears to have little impact on BHMT-dependent remethylation Gallus gallus

Application

Application Comment Organism
additional information in contrast to previous suppositions based on enzyme activity, under most dietary conditions, the quantity of homocysteine remethylated by methionine synthase appeared to exceed that remethylated by the alternate betaine-homocysteine methyltransferase pathway Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-homocysteine + betaine
-
Gallus gallus L-methionine + dimethylglycine
-
?

Synonyms

Synonyms Comment Organism
betaine-homocysteine methyltransferase
-
Gallus gallus
BHMT
-
Gallus gallus