Cloned (Comment) | Organism |
---|---|
glutathione S-transferase-BHMT fusion protein is expressed in HEK-293, T98G, A-10, MCF-7, H-1299, C2C12, and NIH-3T3 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C217A | the mutation reduces zinc binding by 95% while abrogating catalytic activity, the mutation has no effect on the fold increase of GST-BHMT proteolytic fragment in the absence of nutrients | Homo sapiens |
W352A | the mutation disrupts stable BHMT multimerization, the mutant ablates catalytic activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-homocysteine + betaine | - |
Homo sapiens | L-methionine + dimethylglycine | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | - |
Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
betaine homocysteine methyltransferase | - |
Homo sapiens |
BHMT | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | betaine homocysteine methyltransferase is a potential cargo-based end-point marker for macroautophagy | Homo sapiens |