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Literature summary for 2.1.1.5 extracted from

  • Ma, H.; Ning, J.; Jin, X.; Mao, C.; Bu, X.; Wang, M.; Liu, H.; Wang, K.; Lausted, C.; Hood, L.; Chen, J.; Hu, Z.
    Betaine homocysteine methyltransferase (BHMT) as a specific and sensitive blood marker for acute liver injury (2014), Biomarkers, 19, 578-584.
    View publication on PubMed

Application

Application Comment Organism
medicine in serum from healthy individuals, the median value is 1.83 ng/ml. In serum from patients with acute liver injury, the median value of BHMT is 748.48 ng/ml. The detection range of the ELISA assay is from 1.56 to 100 ng/ml with good sensitivity and specificity. In five acute liver injury cases with time course samples available, BHMT and alanine transaminase both follow the rise and fall temporal pattern with the disease progression. The slopes of BHMT curves are steeper than alanine transaminase curves. In three out of the five cases, BHMT levels peak 1 day earlier than alanine transaminase levels Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
blood serum
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Homo sapiens
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