Literature summary for 2.1.1.5 extracted from

Ganu, R.; Garrow, T.; Koutmos, M.; Rund, L.; Schook, L.B.
Splicing variants of the porcine betaine-homocysteine S-methyltransferase gene: implications for mammalian metabolism (2013), Gene, 529, 228-237.

Search for more literature for 2.1.1.5

Crystallization (Commentary)

Crystallization (Comment)	Organism
dominant structural feature of wild type BHMT is an (betaalpha)8 barrel. A modeled structure of truncated BHMT suggests that this protein would assume a horseshoe fold and lack methyltransferase activity	Sus scrofa

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fetus	low BHMT activity is detected in the G30 fetus, and slightly increased levels of activity are observed in the liver from G45 and G90 fetuses	Sus scrofa	-
kidney	transcripts are expressed at significant levels in the liver and kidney from day 45 of gestation onward	Sus scrofa	-
liver	transcripts are expressed at significant levels in the liver and kidney from day 45 of gestation onward	Sus scrofa	-

Expression

Organism	Comment	Expression
Sus scrofa	during fetal development, a total of ten splice variants of BHMT are expressed at varying levels across a wide range of porcine tissues. Two variants contain an identical ORF that encodes a C-terminal truncated form of BHMT	additional information

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Release 2023.1 (January 2023)