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Literature summary for 2.1.1.56 extracted from

  • Cowling, V.H.
    Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformation (2009), Oncogene, 29, 930-936.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.56

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
IMEC cell
-
 Homo sapiens
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mammary epithelial cell line
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + G(5')pppR-RNA
-
 Homo sapiens S-adenosyl-L-homocysteine + m7G(5')pppR-RNA
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 ?

Synonyms

Synonyms Comment Organism
mRNA guanosine cap by RNA guanine-7-methyltransferase
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 Homo sapiens
RNA guanine-7-methyltransferase
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 Homo sapiens
RNMT
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 Homo sapiens

General Information

General Information Comment Organism
physiological function mRNA guanosine cap by RNA guanine-7-methyltransferase is rate-limiting for cellular cap-methyltransferase activity, and enhancing this activity promotes cyclin D1 expression and cell formation Homo sapiens